Dire Wolves Reborn? Scientists Spark Debate with Genetically Engineered Pups
Colossal Biosciences has made headlines with the birth of three genetically engineered wolf pups that the company claims are the world’s first “de-extincted” dire wolves. Using ancient DNA from fossils, scientists edited the genetic material of grey wolves — their closest living relative — to introduce traits like larger skulls, white fur, and powerful jaws. The result? Romulus, Remus, and Khaleesi — pups that look the part, but according to many experts, aren’t truly dire wolves. “It carries dire wolf genes… but across the genome, this is 99.9% gray wolf,” said evolutionary geneticist Love Dalén.
While Colossal insists this represents real de-extinction, critics argue it’s more of a high-tech hybrid than a true resurrection. Dr. Nic Rawlence called the animals “genetically modified grey wolves,” adding that actual dire wolves diverged from grey wolves millions of years ago. Dr. Julie Meachen, who co-authored a paper with Colossal’s chief scientist Beth Shapiro, put it bluntly: “I don't think they are actually dire wolves. What we had is something new.” Shapiro disagrees, claiming the pups fill the dire wolf’s ecological and visual role, saying, “Those are dire wolves.”
The wolves now live at a private 2,000-acre facility, but the project has sparked a broader debate. While some applaud the technology's potential to help endangered species — Colossal also cloned four red wolves using similar methods — others question the ethical and ecological implications. “Extinction is still forever,” Rawlence warned, highlighting fears this might shift focus away from preserving current species. Even supporters like bioethicist Dr. Robert Klitzman urge caution: “You may produce a super wolf… that eats everything in sight.”
